Recent research findings

" Diabetic retinopathy screening in New Zealand requires improvement: results from a multi-centre audit"

AUSTRALIAN AND NEW ZEALAND JOURNAL OF PUBLIC HEALTH

Edward Hutchins
Ophthalmology Section, Department of Medicine, University of Otago, New Zealand
Kirsten J. Coppell
Edgar National Centre for Diabetes and Obesity Research, Department of Medicine, University of Otago, New Zealand
Ainsley Morris
Eye Department, Canterbury District Health Board, New Zealand
Gordon Sanderson
Ophthalmology Section, Department of Medicine, University of Otago, New Zealand

Article

'Effect of intensive control of glucose on cardiovascular outcomes and death in patients with diabetes mellitus: a meta-analysis of randomised controlled trials.'
Lancet. 2009 May 23;373(9677):1765-72.
Ray KK, Seshasai SR, Wijesuriya S, Sivakumaran R, Nethercott S, Preiss D, Erqou S, Sattar N.
Read abstract on Pubmed

'Cardiac outcomes after screening for asymptomatic coronary artery disease in patients with type 2 diabetes: the DIAD study: a randomized controlled trial.'
JAMA. 2009 Apr 15; 301(15): 1547-55.
Young LH, Wackers FJ, Chyun DA, Davey JA, Barrett EJ, et al.; DIAD Investigators.
Read abstract on Pubmed

'Predicting risk of type 2 diabetes in England and Wales: prospective derivation and validation of QDScore.'
BMJ. 2009 Mar 17;338:b880. doi: 10.1136/bmj.b880.
Hippisley-Cox J, Coupland C, Robson J, Sheikh A, Brindle P.
Read abstract on Pubmed

'Long-term effects of metformin on metabolism and microvascular and macrovascular disease in patients with type 2 diabetes mellitus.'
Arch Intern Med. 2009 Mar 23;169(6):616-25.
Kooy A, de Jager J, Lehert P, Bets D, Wulffelé MG, Donker AJ, Stehouwer CD.
Read abstract on Pubmed

'Narrative review: effect of bariatric surgery on type 2 diabetes mellitus.'
Ann Intern Med. 2009 Jan 20;150(2):94-103.
Vetter ML, Cardillo S, Rickels MR, Iqbal N.
Read abstract on Pubmed

'Prevention of diabetes in women with a history of gestational diabetes: effects of metformin and lifestyle interventions.'
J Clin Endocrinol Metab. 2008 Dec;93(12):4774-9.
Ratner RE, Christophi CA, Metzger BE, et al.; Diabetes Prevention Program Research Group
Read abstract on Pubmed

'Intensive versus conventional glucose control in critically ill patients.'
N Engl J Med. 2009 Mar 26; 360(13):1283-97.
NICE-SUGAR Study Investigators, Finfer S, Chittock DR, Su SY, et al.
Read abstract on Pubmed

'Comparison of Weight-Loss Diets with Different Compositions of Fat, Protein, and Carbohydrates.'
N Engl J Med. 2009 Feb 26; 360:859-873.
Sacks FM, Bray GA, Carey VJ, Smith SR, Ryan DH, et al.
Read at NEJM website (free full text available)

'Glucose control and vascular complications in veterans with type 2 diabetes.'
Duckworth W, Abraira C, Moritz T, Reda D; VADT Investigators
N Engl J Med. 2009 Jan 8;360(2):129-39.
Read abstract on Pubmed

'Continuous glucose monitoring and intensive treatment of type 1 diabetes.'
Juvenile Diabetes Research Foundation Continuous Glucose Monitoring Study Group
N Engl J Med. 2008 Oct 2;359(14):1464-76.
Read abstract on Pubmed

'Systematic review: comparative effectiveness and safety of premixed insulin analogues in type 2 diabetes.'
Qayyum R, Bolen S, Maruthur N, Feldman L, Wilson LM, et al.
Ann Intern Med. 2008 Oct 21;149(8):549-59.
Read abstract on Pubmed

'Effectiveness of continuous glucose monitoring in pregnant women with diabetes: randomised clinical trial.'
Murphy HR, Rayman G, Lewis K, Kelly S, Johal B, et al.
BMJ. 2008 Sep 25;337:a1680. doi: 10.1136/bmj.a1680.
Read abstract on Pubmed

'Metformin, sulfonylureas, or other antidiabetes drugs and the risk of lactic acidosis or hypoglycemia: a nested case-control analysis.'
Bodmer M, Meier C, Krähenbühl S, Jick SS, Meier CR.
Diabetes Care. 2008; 31(11):2086-91.
Read abstract on Pubmed

Effect of candesartan on prevention (DIRECT-Prevent 1) and progression (DIRECT-Protect 1) of retinopathy in type 1 diabetes: randomised, placebo-controlled trials.
Chaturvedi N, Porta M, Klein R, Orchard T, Fuller J, Parving HH, Bilous R, Sjølie AK; DIRECT Programme Study Group.
Lancet. 2008 Oct 18;372(9647):1394-402.
Read abstract on Pubmed

Effect of candesartan on progression and regression of retinopathy in type 2 diabetes (DIRECT-Protect 2): a randomised placebo-controlled trial.
Sjølie AK, Klein R, Porta M, Orchard T, Fuller J, Parving HH, Bilous R, Chaturvedi N; DIRECT Programme Study Group.
Lancet. 2008 Oct 18;372(9647):1385-93.
Read abstract on Pubmed

Immunotherapy on trial for new-onset type 1 diabetes.
Faustman, DL.
N Engl J Med 2008; 359: 1956-1958.
Read extract at NEJM website

'Continuous glucose monitoring and intensive treatment of type 1 diabetes.'
Juvenile Diabetes Research Foundation Continuous Glucose Monitoring Study Group.
N Engl J Med. 2008; 359(14):1464-76.
Read abstract on Pubmed

'General and abdominal adiposity and risk of death in Europe.'
Pischon T, Boeing H, Hoffmann K, Bergmann M, Schulze MB, Overvad K, et al.
N Engl J Med. 2008; 359(20):2105-20.
Read abstract on Pubmed

'Exenatide once weekly versus twice daily for the treatment of type 2 diabetes: a randomised, open-label, non-inferiority study.'
Drucker DJ, Buse JB, Taylor K, Kendall DM, Trautmann M, Zhuang D, Porter L; for the DURATION-1 Study Group.
Lancet 2008; 372: 1240–50.
Read abstract on Pubmed

'The prevention of progression of arterial disease and diabetes (POPADAD) trial: factorial randomised placebo controlled trial of aspirin and antioxidants in patients with diabetes and asymptomatic peripheral arterial disease.'
Belch J, MacCuish A, Campbell I, Cobbe S, Taylor R, et al.
BMJ. 2008 Oct 16;337:a1840.
Read abstract on Pubmed

'Aspirin in type 2 diabetes: is there any evidence base?'
Walsh M, Spurling G.
BMJ. 2008 Oct 16;337:a1902.
Read extract at bmj.com 

'Long-Term Follow-up after Tight Control of Blood Pressure in Type 2 Diabetes'
N Engl J Med. 359 (15): 1565-76, Oct 2008.
Holman RR, Paul SK, Bethel MA, Neil HA, Matthews DR.
Read abstract on Pubmed 

10-Year Follow-up of Intensive Glucose Control in Type 2 Diabetes
N Engl J Med. 359 (15): 1577-89, Oct 2008.
Holman RR, Paul SK, Bethel MA, Matthews DR, Neil HA.
Read abstract on Pubmed 

Role of blood pressure in development of early retinopathy in adolescents with type 1 diabetes: prospective cohort study.
BMJ. 337:a918. doi: 10.1136/bmj.a918, Aug 2008.
Gallego PH, Craig ME, Hing S, Donaghue KC.
Read article at BMJ website (free full text) 

Screening for type 2 diabetes mellitus in adults: U.S. Preventive Services Task Force recommendation statement.
Ann Intern Med. 148 (11): 846-54, June 2008.
U.S. Preventive Services Task Force.
Read abstract on Pubmed 

Renal outcomes with telmisartan, ramipril, or both, in people at high vascular risk (the ONTARGET study): a multicentre, randomised, double-blind, controlled trial.
Lancet. 372 (9638): 547-53, August 2008.
Mann JF, Schmieder RE, McQueen M, Dyal L et al.; ONTARGET investigators.
Read abstract on Pubmed
Editorial comment regarding the ONTARGET study (subscription required) 

'Consensus Statement: A New Look at Screening and Diagnosing Diabetes Mellitus '
J Clin Endocrinol Metab. 93: 2447-2453, July 2008.
Christopher D. Saudek, William H. Herman, David B. Sacks, Richard M. Bergenstal, David Edelman, and Mayer B. Davidson
Read abstract on Pubmed 

'Adherence to Mediterranean diet and risk of developing diabetes: prospective cohort study.'
BMJ. 336 (7657): 1348-51, June 14, 2008.
Martinez-Gonzalez MA. de la Fuente-Arrillaga C. Nunez-Cordoba JM. Basterra-Gortari FJ. Beunza JJ. Vazquez Z. Benito S. Tortosa A. Bes-Rastrollo M.
Read abstract on Pubmed 

'Cost effectiveness of self monitoring of blood glucose in patients with non-insulin treated type 2 diabetes: economic evaluation of data from the DiGEM trial.'
BMJ. 336 (7654): 1177-1180, May 24, 2008
Judit Simon, Alastair Gray, Philip Clarke, Alisha Wade, Andrew Neil, Andrew Farmer on behalf of the Diabetes Glycaemic Education and Monitoring Trial Group
Read abstract on Pubmed 

'Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes.'
N Engl J Med . 358(24):2560-72, June 12, 2008
ADVANCE Collaborative Group, Patel A, MacMahon S, Chalmers J, Neal B, et al .
Read abstract on PubMed
Editorial comment by Dluhy & McMahon at NEJM
Editorial comment by Cefalu at NEJM (free full text) 

'Effects of intensive glucose lowering in type 2 diabetes.'
N Engl J Med . 358(24):2545-59, June 12, 2008
Action to Control Cardiovascular Risk in Diabetes Study Group, Gerstein HC, Miller ME, Byington RP, Goff DC Jr, Bigger JT, Buse JB, Cushman WC, Genuth S, Ismail-Beigi F, Grimm RH Jr, Probstfield JL, Simons-Morton DG, Friedewald WT.
Read abstract on PubMed
Editorial comment by Dluhy & McMahon at NEJM
Editorial comment by Cefalu at NEJM (free full text) 

'Time trends in the incidence of type 1 diabetes in Finnish children: a cohort study.'
Lancet 371(9626): 1777-82, May 24, 2008
Harjutsalo V, Sjöberg L, Tuomilehto J.
Read abstract on PubMed 

'Effect of intensive insulin therapy on beta-cell function and glycaemic control in patients with newly diagnosed type 2 diabetes: a multicentre randomised parallel-group trial.'
Lancet 371(9626): 1753-60, May 24, 2008
Weng J, Li Y, Xu W, Shi L, Zhang Q, Zhu D, Hu Y, Zhou Z, Yan X, Tian H, Ran X, Luo Z, Xian J, Yan L, Li F, Zeng L, Chen Y, Yang L, Yan S, Liu J, Li M, Fu Z, Cheng H
Read abstract on PubMed 

'The long-term effect of lifestyle interventions to prevent diabetes in the China Da Qing Diabetes Prevention Study: a 20-year follow-up study.'
Lancet 371 :1783-1789, 24 May, 2008
Li G, Zhang P, Wang J, Gregg EW, Yang W, Gong Q, Li H, Li H, Jiang Y, An Y, Shuai Y, Zhang B, Zhang J, Thompson TJ, Gerzoff RB, Roglic G, Hu Y, Bennett PH.
Read abstract on PubMed 

'Metformin versus insulin for the treatment of gestational diabetes.'
N Engl J Med 358(19):2003-15, May 8, 2008
Rowan JA, Hague WM, Gao W, Battin MR, Moore MP; MiG Trial Investigators.
Read abstract on PubMed 

NZSSD Expert Opinion comment on the MiG trial (24KB)

'Hyperglycemia and adverse pregnancy outcomes.'
N Engl J Med 358(19):1991-2002, May 8, 2008
HAPO Study Cooperative Research Group, Metzger BE, Lowe LP, Dyer AR, Trimble ER, Chaovarindr U, Coustan DR, Hadden DR, McCance DR, Hod M, McIntyre HD, Oats JJ, Persson B, Rogers MS, Sacks DA.
Read abstract on PubMed 

NZSSD Expert Opinion comment on the HAPO study (24KB)

'Once-daily basal insulin glargine versus thrice-daily prandial insulin lispro in people with type 2 diabetes on oral hypoglycaemic agents (APOLLO): an open randomised controlled trial.'
Lancet 371(9618):1073-84, March 29, 2009
Bretzel RG, Nuber U, Landgraf W, Owens DR, Bradley C, Linn T
Read abstract on PubMed 

'Effect of a Multifactorial Intervention on Mortality in Type 2 Diabetes'
N Engl J Med 358:580-91, February 7, 2008
Gaede P, Lund-Andersen H, Parving HH, Pedersen O
Read abstract on PubMed 

'Addition of Biphasic, Prandial, or Basal Insulin to Oral Therapy in Type 2 Diabetes'
N Engl J Med 357:1716-30, October 25, 2007
Holman RR, Thorne KI, Farmer AJ, Davies MJ, Keenan JF, Paul S, Levy JC
Read abstract on PubMed 

'Meta-analysis: Effect of Monotherapy and Combination Therapy with Inhibitors of the Renin–Angiotensin System on Proteinuria in Renal Disease'
Ann Intern Med 148:30-48, 2008
Kunz R, Friedrich C, Wolbers M, Mann JFE
Read abstract on PubMed 

'Adjustable Gastric Banding and Conventional Therapy for Type 2 Diabetes: A Randomized Controlled Trial'
JAMA 299(3):316-323, 2008
Dixon JB, O'Brien PE, Playfair J, Chapman L, Schachter LM, Skinner S, Proietto J, Bailey M, Anderson M
Read abstract on PubMed